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Carbamazepine differentially affects the pharmacokinetics of fexofenadine enantiomers

โœ Scribed by Yumiko Akamine; Masatomo Miura; Norio Yasui-Furukori; Midori Kojima; Tsukasa Uno

Book ID
108642793
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
576 KB
Volume
73
Category
Article
ISSN
0306-5251

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Reboxetine, (RS)-2-[(RS)-alpha-(2-ethoxyphenoxy)benzyl]morpholine methanesulphonate, is a racemic compound and consists of a mixture of the (R,R)- and (S,S)-enantiomers. The pharmacokinetics of reboxetine enantiomers were determined in a crossover study in three male beagle dogs. Each animal receive