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Carbamazepine and Polyethylene Glycol Solid Dispersions: Preparation, in Vitro Dissolution, and Characterization

✍ Scribed by Doshi, D. H.; Ravis, W. R.; Betageri, G. V.

Book ID
118015519
Publisher
Informa plc
Year
1997
Tongue
English
Weight
645 KB
Volume
23
Category
Article
ISSN
0363-9045

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The dissolution characteristics of dicumarol were markedly enhanced by preparing dispersions of drug in polyethylene glycol 4000. Solid dispersions of varying weight fractions were formed by a melt method without measurable drug degradation or evaporation. There were no significant differences in di