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Solid dispersions of nimodipine and polyethylene glycol 2000: dissolution properties and physico-chemical characterisation

✍ Scribed by Nora Anne Urbanetz; Bernhard Christian Lippold

Book ID
116437325
Publisher
Elsevier Science
Year
2005
Tongue
French
Weight
329 KB
Volume
59
Category
Article
ISSN
0939-6411

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The dissolution characteristics of dicumarol were markedly enhanced by preparing dispersions of drug in polyethylene glycol 4000. Solid dispersions of varying weight fractions were formed by a melt method without measurable drug degradation or evaporation. There were no significant differences in di