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Capturing the Initial Autocatalytic Maturation Mechanism of HIV-1 protease at Atomic Resolution

✍ Scribed by Sadiq, S. Kashif; De Fabritiis, Gianni


Book ID
122116780
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
35 KB
Volume
100
Category
Article
ISSN
0006-3495

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Peptidomimetic inhibitors of human immunodeficiency virus-1 protease are successful lead substances for the development of virostatic drugs against HIV as the causative agent of acquired immunodeficiency syndrome (AIDS). The hydroxyethylamine isostere of the proteolytic cleavage intermediate provide