Synthesis on soluble polymers: new react
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Dennis J Gravert; Kim D Janda
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Article
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1997
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Elsevier Science
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English
β 712 KB
To avoid the heterogeneous reaction conditions of solid-phase chemistry, liquid-phase synthesis provides homogeneity through the use of soluble polymer supports that can be selectively precipitated and filtered to achieve product purification. Peptides, oligonucleotides, and oligosaccharides have be