Capillary-Scale Refractive Index Detection by Interferometric Backscatter
β Scribed by Tarigan, Hendra J.; Neill, Paul; Kenmore, Christopher K.; Bornhop, Darryl J.
- Book ID
- 126335427
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 323 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0003-2700
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π SIMILAR VOLUMES
We describe a method for determining subpicomole quantities of analyte in capillary electrophoresis by probing fluid bulk properties with laser interferometric backscatter. In micro-interferometric backscatter detection Ε½ . MIBD , an unfocused beam from a He-Ne laser impinges onto unmodified fused s
An existing commercial refractive index detector was modified for use with slurry-packed capillary column LC systems. The cell gasket of the original detector cell was replaced by a micro cell gasket giving a volume of 0.8 pL. The relationship between detector response and the amount of sample injec