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Capillary electrophoretic chiral determination of mirtazapine and its main metabolites in human urine after enzymatic hydrolysis

✍ Scribed by Fernando José Malagueño de Santana; Vera Lúcia Lanchote; Pierina Sueli Bonato


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
174 KB
Volume
29
Category
Article
ISSN
0173-0835

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## Abstract A simple, rapid, and sensitive procedure using nonaqueous capillary electrophoresis (NACE) to measure Paroxetine (one of the mostly used antidepressants for mental diseases treatment) and three metabolites has been developed and validated. Optimum separation of paroxetine and metabolite