𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Capillary electrophoresis of amphipathic α-helical peptide diastereomers

✍ Scribed by Traian V. Popa; Colin T. Mant; Robert S. Hodges

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
202 KB
Volume
25
Category
Article
ISSN
0173-0835

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mode of action of linear amphipathic α-h
Mode of action of linear amphipathic α-helical antimicrobial peptides
✍ Ziv Oren; Yechiel Shai 📂 Article 📅 1998 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 222 KB

The increasing resistance of bacteria to conventional antibiotics resulted in a strong effort to develop antimicrobial compounds with new mechanisms of action. Antimicrobial peptides seem to be a promising solution to this problem. Many studies aimed at understanding their mode of action were descri

Structural requirements for cellular upt
Structural requirements for cellular uptake of α-helical amphipathic peptides
✍ Anne Scheller; Johannes Oehlke; Burkhard Wiesner; Margitta Dathe; Eberhard Kraus 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB 👁 1 views

The structure of the cell-permeable h-helical amphipathic model peptide FLUOS-KLALKLALKA-LKAALKLA-NH 2 (I) was modified stepwise with respect to its helix parameters hydrophobicity, hydrophobic moment and hydrophilic face as well as molecular size and charge. Cellular uptake and membrane destabilizi

Candidacidal mechanism of a Leu/Lys-rich
Candidacidal mechanism of a Leu/Lys-rich α-helical amphipathic model antimicrobial peptide and its diastereomer composed of D,L-amino acids
✍ Peng Wang; Yong Hai Nan; Song Yub Shin 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 854 KB

## Abstract We investigated the mechanism of candidacidal action of a Lys/Leu‐rich α‐helical model antimicrobial peptide (K~9~L~8~W) and its diastereomeric peptide (D~9~‐K~9~L~8~W) composed of D,L‐amino acids. K~9~L~8~W killed completely __Candida albicans__ within 30 min, but D~9~‐K~9~L~8~W killed

Resolution of the diastereomers of a lar
Resolution of the diastereomers of a large synthetic peptide by capillary electrophoresis using nonionic surfactants
✍ Dr. Martin Gilges; Mark Hadley 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 512 KB

## Abstract A capillary electrophoretic method was developed for the determination of the diastereomeric composition of the bradykinin B~2~ antagonist, SB‐238592‐DB. The nonionic surfactant Brij 35 was demonstrated to be suitable for the baseline resolution of the three diastereoisomers of SB‐23859