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Capillary electrophoresis method for plasmatic determination of imatinib mesylate in chronic myeloid leukemia patients

✍ Scribed by Tatiana O. Ajimura; Keyller B. Borges; Aline F. Ferreira; Fabíola A. de Castro; Cristiane M. de Gaitani


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
174 KB
Volume
32
Category
Article
ISSN
0173-0835

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## Abstract ## BACKGROUND. Lonafarnib is an orally bioavailable nonpetidomimetic farnesyl transferase inhibitor with significant activity against BCR‐ABL‐positive cell lines and primary human chronic myeloid leukemia (CML) cells. Lonafarnib can inhibit the proliferation of imatinib‐resistant cells