Capillary electrophoresis-mass spectrometry for the analysis of amino acids

✍ Scribed by Claudia Desiderio; Federica Iavarone; Diana Valeria Rossetti; Irene Messana; Massimo Castagnola

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 297 KB
• Volume: 33
• Category: Article
• ISSN: 1615-9306
• DOI: 10.1002/jssc.201000171

✦ Synopsis

Abstract

In this review, the recent contribution of CE‐MS technology to the analysis of amino acids, as well as the advantages of the hyphenation and the technologies involved in the instrumental coupling are reported. Different sections are dedicated to the recent contributions of CE‐MS to the analysis of protein amino acids and their post‐translational modifications, such as phosphorylation and sulfation. CE‐MS analysis of some amino acid derivatives, such as the free methylated‐derivatives of arginine is also discussed. A section is specifically devoted to the CE‐MS applications in the field of chiral separation of D‐ and L‐amino acid enantiomers.