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Capecitabine Therapy of Central Nervous System Metastases from Breast Cancer

✍ Scribed by Meltem Ekenel; Adilia M. Hormigo; Scott Peak; Lisa M. DeAngelis; Lauren E. Abrey

Publisher: Springer US
Year: 2007
Tongue: English
Weight: 239 KB
Volume: 85
Category: Article
ISSN: 0167-594X
DOI: 10.1007/s11060-007-9409-0

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## Abstract ## BACKGROUND Trastuzumab, which is a large monoclonal antibody that is efficacious in the treatment of patients with HER‐2/__neu__‐overexpressing, metastatic breast carcinoma, does not penetrate the blood‐brain barrier and, thus, may allow the brain to become a sanctuary site for micr