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Cancers of unknown primary origin: current perspectives and future therapeutic strategies

✍ Scribed by Giulia Maria Stella; Rebecca Senetta; Adele Cassenti; Margherita Ronco; Paola Cassoni

Book ID
115020890
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
347 KB
Volume
10
Category
Article
ISSN
1479-5876

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MET mutations in cancers of unknown prim
MET mutations in cancers of unknown primary origin (CUPs)
✍ Giulia M. Stella; Silvia Benvenuti; Daniela Gramaglia; Aldo Scarpa; Anna Tomezzo πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 278 KB

Cancer of unknown primary origin (CUP) defines metastatic disease of unknown origin, accounting for 3-5% of all cancers. Growing evidence demonstrates that inappropriate execution of a genetic program named ''invasive growth,'' driven by the MET oncogene, is implicated in the metastatic process. MET