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Cancer stem-like cells and epithelial-mesenchymal transition—utility of biomarkers in diagnostic pathology

✍ Scribed by Lloyd, Ricardo V.

Book ID: 120590733
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 98 KB
Volume: 44
Category: Article
ISSN: 1532-8392
DOI: 10.1016/j.humpath.2013.05.002

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## Abstract Cancer stem cells (CSCs) are similar to normal stem cells in their ability to self‐renew and to generate large populations of more differentiated descendants. In contrast to the hierarchical organization that is presumed to be the prevalent mode of normal tissue homeostasis, phenotypic