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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

โœ Scribed by Schiffelers, R. M.


Book ID
125812879
Publisher
Oxford University Press
Year
2004
Tongue
English
Weight
561 KB
Volume
32
Category
Article
ISSN
0305-1048

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Systemic delivery of siRNA specific to t
โœ Ping Mu; Shunji Nagahara; Naoki Makita; Yuzo Tarumi; Kenji Kadomatsu; Yoshifumi ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 816 KB

## Abstract The largest obstacle to the effective use of short interfering RNA (siRNA) in an animal body is the ability to deliver it to the target tissue. Here we showed a systemic delivery method of siRNA specific to pregrown solid tumors __via__ atelocollagen. Atelocollagen facilitated the selec