Cancer in twins of Wilms tumor patients
β Scribed by Olson, Jane M. ;Breslow, Norman E. ;Barce, Jean
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 425 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0148-7299
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We conducted a comparative study of the prevalence of gerrnline WTI mutations in patients with Wilms' tumor. Patients in Group l have familial Wilms' tumor, bilateral disease, associated urogenital anomalies, and/or second cancers. Those in Group 2 are unilateral, sporadic Wilrns' patients without o
## Abstract The WAGR contiguous gene deletion syndrome is a combination of Wilms tumor, Aniridia, Genitoβurinary abnormalities, and growth and mental retardation which is invariably associated with an 11p13 deletion. We report two monozygotic twins and a third, unrelated patient with WAGR syndrome
The case of a 7-year-old boy presenting at diagnosis with a localized (stage 111) Wilms' tumor of favorable histology is presented. lmmunocytologic analysis of bone marrow aspirates revealed cells positive for neural cell adhesion molecule (NCAM) and negative for class I major histocompatibility com