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Cancer gets Mad: DPC4 and other TGFβ pathway genes in human cancer

✍ Scribed by Christopher A. Moskaluk; Scott E. Kern

Book ID
114222904
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
238 KB
Volume
1288
Category
Article
ISSN
0304-419X

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## Abstract Human Cripto‐1 (CR‐1) is a cell membrane protein that is overexpressed in several different types of human carcinomas. In the present study we investigated the mechanisms that regulate the expression of CR‐1 gene in cancer cells. We cloned a 2,481 bp 5′‐flanking region of the human CR‐1