Cancer antigens: immune recognition of self and altered self
β Scribed by Houghton, Alan N. (author)
- Book ID
- 125514495
- Publisher
- Rockefeller University Press.
- Year
- 1994
- Tongue
- English
- Weight
- 331 KB
- Volume
- 180
- Category
- Article
- ISSN
- 0022-1007
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Recent studies have increased our understanding of the nature of autoimmune recognition and of the identity of autoantigens, at least in model systems. Knowledge of the autoantigens and the process of recognition is suggesting new therapies for autoimmune disease.
## Abstract Fluorescein (FITC)βhaptenated mouse spleen cells are capable of inducing a B cell immune response characterized by the production of antibodies directed against haptenβaltered self structures. The induction of this response is thymusβindependent and strictly dependent on the hapten conc