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Can paraoxonase 1 polymorphisms (L55 M and Q192 R) protect children with type 1 diabetes against lipid abnormalities?

✍ Scribed by Fekih, Ons; Triki, Sonia; Hellara, Ilhem; Neffati, Fadoua; Rejeb, Jihen; Ommezzine, Asma; Chouchane, Slaheddine; Guediche, Mohamed Neji; Bouslama, Ali; Najjar, Mohamed Fadhel


Book ID
122178259
Publisher
Elsevier
Year
2014
Tongue
English
Weight
174 KB
Volume
8
Category
Article
ISSN
1933-2874

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A preliminary study of human paraoxonase
✍ Dilara Kaman; Necip İlhan; Kerem Metin; Mehmet Akbulut; Bilal Üstündağ 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB

## Abstract Paraoxonase 1 (PON 1) is a high‐density lipoprotein (HDL)‐associated enzyme with antioxidant function protecting low‐density lipoprotein (LDL) from oxidation. PON 1 has two amino acid polymorphisms in coding region; L/M 55 and Q/R 192. These polymorphisms modulate paraoxonase activity o