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Can lesions to the motor cortex induce amyotrophic lateral sclerosis?

✍ Scribed by Rosenbohm, Angela; Kassubek, Jan; Weydt, Patrick; Marroquin, Nicolai; Volk, Alexander E.; Kubisch, Christian; Huppertz, Hans-Jürgen; Weber, Markus; Andersen, Peter M.; Weishaupt, Jochen H.; Ludolph, Albert C.

Book ID
121557104
Publisher
Springer
Year
2013
Tongue
English
Weight
260 KB
Volume
261
Category
Article
ISSN
0340-5354

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The motor cortex and amyotrophic lateral
The motor cortex and amyotrophic lateral sclerosis
✍ Andrew Eisen; Markus Weber 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB

## Abstract On theoretical grounds, abnormalities of the motor cortex in patients with amyotrophic lateral sclerosis (ALS) could lead to anterograde (“dying‐forward”) transneuronal degeneration of the anterior horn cells as suggested by Charcot. Conversely, retrograde (“dying‐back”) degeneration of