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CAMKII modulates cardiac excitation contraction coupling at multiple sites in ovine cardiac myocytes

✍ Scribed by Jessica D. Clarke; Leonie C. Diffley; Katharine M. Dibb; David A. Eisner; Andrew W. Trafford


Book ID
116984040
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
54 KB
Volume
40
Category
Article
ISSN
0022-2828

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## Abstract Intracellular Na^+^ concentration ([Na^+^]~i~) is very important in modulating the contractile and electrical activity of the heart. Upon electrical excitation of the myocardium, voltage‐dependent Na^+^ channels open, triggering the upstroke of the action potential (AP). During the AP,