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Alterations in action potential profile enhance excitation-contraction coupling in rat cardiac myocytes

✍ Scribed by Rajan Sah; Rafael J. Ramirez; Roger Kaprielian; Peter H. Backx

Book ID
111119731
Publisher
Cambridge University Press
Year
2001
Tongue
English
Weight
227 KB
Volume
533
Category
Article
ISSN
0022-3751

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📜 SIMILAR VOLUMES

Na+ transport in cardiac myocytes; Impli
Na+ transport in cardiac myocytes; Implications for excitation-contraction coupling
✍ Donald M. Bers; Sanda Despa 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB

## Abstract Intracellular Na^+^ concentration ([Na^+^]~i~) is very important in modulating the contractile and electrical activity of the heart. Upon electrical excitation of the myocardium, voltage‐dependent Na^+^ channels open, triggering the upstroke of the action potential (AP). During the AP,