Tiazofurin is an interesting drug now entering Phase I trials, with marked preclinical antitumor activity against P388 and L1210 leukemias, and the Lewis lung carcinoma. Schedule dependency favoring frequent administration has been noted. The drug has a novel mechanism of action, being metabolized
β¦ LIBER β¦
Calvacin: A New Antitumor Agent
β Scribed by Roland, J. F.; Chmielewicz, Z. F.; Weiner, B. A.; Gross, A. M.; Boening, O. P.; Luck, J. V.; Bardos, T. J.; Reilly, H. C.; Sugiura, K.; Stock, C. C.; Lucas, E. H.; Byerrum,, R. U.; Stevens, J. A.
- Book ID
- 121166736
- Publisher
- American Association for the Advancement of Science
- Year
- 1960
- Tongue
- English
- Weight
- 272 KB
- Volume
- 132
- Category
- Article
- ISSN
- 0036-8075
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Tiazofurin: A new antitumor agent
β
Peter J. O'Dwyer; D. Dale Shoemaker; Hiremagalur N. Jayaram; David G. Johns; Dav
π
Article
π
1984
π
Springer US
π
English
β 481 KB
New antitumor agent β Spirobromin
β
T. S. Safonova; V. A. Chernov; S. M. Minakova; M. I. Dorokhova; L. G. Levkovskay
π
Article
π
1983
π
Springer
π
English
β 265 KB
9-DeazaadenosineβA new potent antitumor
β
Ming Y. Chu; Linda B. Zuckerman; Seiji Sato; Gerald W. Crabtree; Arthur E. Bogde
π
Article
π
1984
π
Elsevier Science
π
English
β 764 KB
Quadrone, a new antitumor agent from asp
β
R.L. Ranieri; G.J. Calton
π
Article
π
1978
π
Elsevier Science
π
French
β 182 KB
Clastogenic activity of FK973, a new ant
β
Y. Miyamae; O. Hirai; K. Ohara; M. Hashimoto; A. Tensho
π
Article
π
1988
π
Elsevier Science
π
English
β 78 KB
Experimental antitumor activity of BMY-2
β
John E. Schurig; William C. Rose; Hideo Kamei; Yuji Nishiyama; William T. Bradne
π
Article
π
1990
π
Springer US
π
English
β 586 KB
BMY-28175 is a novel antitumor antibiotic produced in fermentation by Actinomadura verrucosospora. The cytotoxic effects of BMY-28175 were determined using murine and human tumor cell lines in vitro. Following 72 hour exposure, the drug had IC50 values 1.5 to 13.5 ng/ml in a microtiter assay. BMY-28