Sensing, signaling, and responding to DN
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Lei Li; Lee Zou
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Article
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2005
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John Wiley and Sons
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English
β 145 KB
The DNA damage and replication checkpoints are signaling mechanisms that regulate and coordinate cellular responses to genotoxic conditions. Unlike typical signal transduction mechanisms that respond to one or a few stimuli, checkpoints can be activated by a broad spectrum of extrinsically or intrin