Calnexin expression does not enhance the generation of MHC class I-peptide complexes
✍ Scribed by Shiv A. Prasad; Jonathan W. Yewdell; Angel Porgador; Bhanu Sadasivan; Peter Cresswell; Jack R. Bennink
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 165 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0014-2980
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## Abstract Major histocompatibility complex (MHC) class I and II molecules present antigenic fragments to the immune system. MHC‐like chaperones, like HLA‐DM, HLA‐DO and tapasin support peptide loading. HLA class I heavy chains require association with β2‐microglobulin and peptide for endoplasmic