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Calmodulin involvement in TPA and DDT induced inhibition of intercellular communication

✍ Scribed by Lars Wärngård; Ronny Fransson; Tor Björn Drakenberg; Sten Flodström; Ulf G. Ahlborg


Book ID
113137092
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
479 KB
Volume
65
Category
Article
ISSN
0009-2797

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## Abstract The phorbol ester, 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA), is a potent inhibitor of gap junctional intercellular communication (GJIC). This inhibition requires activation of protein kinase C (PKC), but the events downstream of this kinase are not known. Since PKC can activate ex