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Calicheamicin θ: A Rationally Designed Molecule with Extremely Potent and Selective DNA Cleaving Properties and Apoptosis Inducing Activity

✍ Scribed by Prof. Dr. K. C. Nicolaou; Dr. T. Li; Masahisa Nakada; Conrad W. Hummel; A. Hiatt; W. Wrasidlo

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 520 KB
Volume: 33
Category: Article
ISSN: 0044-8249
DOI: 10.1002/anie.199401831

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Fig. 1. Molecular structure of 10 in the crystal (ORTEP) with the thermal ellipsoids at the 10% probability level for the non-hydrogen atoms. The estimated standard deviations are 0.009-0.01 1 A and 0.7-0.8" for bond distances