## Abstract A new method is presented for the calculation of partition coefficients of solutes in water lipid systems. Log __P__ values are calculated based on the charge densities of the atoms as determined by quantum mechanical methods. In this article, the results have been obtained from charge
โฆ LIBER โฆ
Calculating Partition Coefficients of Peptides by the Addition Method
โ Scribed by Peng Tao; Renxiao Wang; Luhua Lai
- Publisher
- Springer-Verlag
- Year
- 1999
- Tongue
- English
- Weight
- 148 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1610-2940
No coin nor oath required. For personal study only.
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The values of log10 P (partition coefficient, in octanollwater) were calculated for about 200 organic molecules of diverse structures and functionalities. The method involves a simple procedure and appears accurate enough for semiquantitative applications. Further, this method of calculating loglo P