## Abstract BRCA1 is a multifunctional tumorβsuppressive protein. Many functional aspects of BRCA1 are not fully understood. We used a shRNA approach to probe the function of BRCA1 in human breast cancer cells. Knocking down BRCA1 expression by shRNA in the wildβtype BRCA1 human breast cancer MCFβ7
β¦ LIBER β¦
Calcium sensing receptor down-regulates malignant cell behavior and promotes chemosensitivity in human breast cancer cells
β Scribed by Guangming Liu; Xin Hu; Subhas Chakrabarty
- Book ID
- 113525778
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 860 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0143-4160
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## Abstract Radiographic mammary microcalcifications are one of the most pertinent diagnostic markers of breast cancer. Breast tissue calcification in the form of calcium hydroxyapatite (HA) is strongly associated with malignant disease. We tested the hypothesis that calcium HA may exert biological