𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Calcium inhibition of the activation of protein C by thrombin Role of the P3 and P3′ residues

✍ Scribed by Alireza R. REZAIE; Charles T. ESMON

Book ID
115130938
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
564 KB
Volume
223
Category
Article
ISSN
1432-1327

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Charge reversal at the P3′ position in p
Charge reversal at the P3′ position in protein C optimally enhances thrombin affinity and activation rate
✍ Mark A. Richardson; Bruce Gerlitz; Brian W. Grinnell 📂 Article 📅 2008 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 218 KB

## Abstract We have examined the properties of several human protein C (HPC) derivatives with substitutions for acidic residues near the thrombin cleavage site, including changing the P3′ Asp to Asn (D172N), Gly (D172G), Ala (D172A), or Lys (D172K). The rate of thrombin‐catalyzed activation of D172