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Calcium-binding properties of skeletal muscle microsomes

✍ Scribed by Sampson, Sanford R. ;Karler, Ralph

Publisher
Wiley (John Wiley & Sons)
Year
1963
Tongue
English
Weight
501 KB
Volume
62
Category
Article
ISSN
0095-9898

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✦ Synopsis

cology Training Grant (26-153), and a research career program award (NB-K3-8641-R1) from the National Institute of Neurological Diseases and Blindness, National Institutes of Health.

2 Recent studies (Hasselbach and Makinose, '61; Ebashi and Lipmann, '62) concerning. the blnding of C a + + by the granules of the relaxing factor has shown that these particles believed to be derived from the SR can "pump" % a + + i n the presence of ATP. These korkers propose that the Ca f + accumulation by the relaxing factor is involved i n the rcactions of muscle relaxation However present concepts of the function of the 'SR impliiate this structure in e,xcitation-contraction coupling rather than in relaxation.

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