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Calcitonin receptor-stimulating peptide-1 regulates ion transport and growth of renal epithelial cell line LLC-PK1

โœ Scribed by Kazumasa Hamano; Takeshi Katafuchi; Katsuro Kikumoto; Naoto Minamino


Book ID
116290151
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
249 KB
Volume
330
Category
Article
ISSN
0006-291X

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LLC-PK1 and M D C K cells take up cationic amino acids (lysine and arginine) by a specific sodium independent transport system. Uptake is inhibited by ornithine in LLC-PK, and M D C K cells either in t h e presence or absence of sodium and by glutamine or homoserine in M D C K cells in the presence

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## Abstract Uptake of ฮฑโ€methylโ€Dโ€glucoside (AMG) by LLCโ€PK~1~ cells is inhibited by the uncoupler pโ€trifluoroโ€methoxyphenylโ€hydrazone (FCCP) and by the absence of extracellular Na^+^, indicating that the transport system is energyโ€ and Na^+^ โ€dependent. We have previously demonstrated that transpor