## Abstract Uptake of α‐methyl‐D‐glucoside (AMG) by LLC‐PK~1~ cells is inhibited by the uncoupler p‐trifluoro‐methoxyphenyl‐hydrazone (FCCP) and by the absence of extracellular Na^+^, indicating that the transport system is energy‐ and Na^+^ ‐dependent. We have previously demonstrated that transpor
Cadmium uptake and induction of metallothionein synthesis in a renal epithelial cell line (LLC-PK1)
✍ Scribed by E. Felley-Bosco; J. Diezi
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 383 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0340-5761
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Cyclosporine A (CSA) is an effective immunosuppressant, but side effects such as renal toxicity can limit its therapeutic use. The current studies investigate the effects of lipoproteins on CSA-induced renal toxicity in the pig epithelial cell line LLC-PK 1 . Protein synthesis and tritiated CSA were
## Abstract The__V__~max~values (in nmol/mg protein/15 min) for AAAD in OK cells (0.94±0.08) were found to be significantly (__P__<0.01) lower than those observed in LLC‐PK~1~cells (4.37±0.08). However, in both cell lines decarboxylation reaction was a saturable process with similar__K__~m~values (