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Calcitonin gene-related peptide enhances calcium current of rat dorsal root ganglion neurons and spinal excitatory synaptic transmission

✍ Scribed by Ryu, P.D.; Gerber, G.; Murase, Kazuyuki; Randic, M.

Book ID: 123267646
Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 406 KB
Volume: 89
Category: Article
ISSN: 0304-3940
DOI: 10.1016/0304-3940(88)90544-7

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## Abstract Calcitonin gene‐related peptide (CGRP) is synthesized in dorsal root ganglion (DRG) neurons and released from primary afferent neurons to mediate hemodynamic effects and neurogenic inflammation. The effect of the proinflammatory cytokine interleukin‐1 (IL‐1)‐β on CGRP release from these