Calcineurin inhibitors in renal transplantation: adverse effects
โ Scribed by Matthew Jose
- Book ID
- 108960319
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 82 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1320-5358
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Although calcineurin inhibitors (CNIs) remain the mainstay of immunosuppression in liver transplantation (LTX), their long-term toxicity significantly contributes to morbidity and mortality. The elucidation of mechanisms of alloimmunity and leukocyte migration have provided novel targets for immunos
Calcineurin inhibitors (CNIs) are the cornerstone of immunosuppression after liver transplantation. However, CNI treatment is frequently associated with chronic renal failure (CRF). The reduction or interruption of CNI may reduce renal failure. We prospectively studied 49 liver recipients treated wi