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Calbindin D28K as a marker for the degeneration of the striatonigral pathway in Huntington's disease

✍ Scribed by H. Kiyama; A. Seto-Ohshima; P.C. Emson

Book ID
115800734
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
851 KB
Volume
525
Category
Article
ISSN
0006-8993

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## Abstract Activating the ERK pathway (extracellular signal‐regulated kinase pathway) has proven beneficial in several models of Huntington's disease (HD), and drugs that are protective in HD models have recently been found to activate ERK. Thus, the ERK cascade may be a potential target for thera