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A novel target for Huntington's disease: ERK at the crossroads of signaling : The ERK signaling pathway is implicated in Huntington's disease and its upregulation ameliorates pathology

✍ Scribed by Bodai, László (author);Marsh, J. Lawrence (author)

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
300 KB
Volume
34
Category
Article
ISSN
0265-9247

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A novel target for Huntington's disease:
A novel target for Huntington's disease: ERK at the crossroads of signaling : The ERK signaling pathway is implicated in Huntington's disease and its upregulation ameliorates pathology
✍ Bodai, László (author);Marsh, J. Lawrence (author) 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 300 KB 👁 1 views

## Abstract Activating the ERK pathway (extracellular signal‐regulated kinase pathway) has proven beneficial in several models of Huntington's disease (HD), and drugs that are protective in HD models have recently been found to activate ERK. Thus, the ERK cascade may be a potential target for thera