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Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation

✍ Scribed by Zhan-Guo Gao; Béatrice Hechler; Pedro Besada; Christian Gachet; Kenneth A. Jacobson

Book ID
113488438
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
457 KB
Volume
75
Category
Article
ISSN
0006-2952

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## Abstract The recent generation of mice deficient for the P2Y~1~ receptor has allowed us to directly examine the contribution of this nucleotide receptor in ADP‐induced aggregation both in isolated platelets and in vivo thrombosis. Studies utilizing the P2Y~1~‐deficient platelets clearly demonstr