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ADP can induce aggregation of human platelets via both P2Y1 and P2T receptors

✍ Scribed by G E Jarvis; R G Humphries; M J Robertson; P Leff


Book ID
110004753
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
278 KB
Volume
129
Category
Article
ISSN
0007-1188

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## Abstract The recent generation of mice deficient for the P2Y~1~ receptor has allowed us to directly examine the contribution of this nucleotide receptor in ADP‐induced aggregation both in isolated platelets and in vivo thrombosis. Studies utilizing the P2Y~1~‐deficient platelets clearly demonstr