The effects of the mycotoxin citrinin on renal cortical and liver mitochondrial swelling were studied. Citrinin decreases the rate of swelling induced by the valinomycin-K+ complex, suggesting that the mycotoxin interferes with the mitochondrial membrane fluidity. Citrinin promotes reduction of the
✦ LIBER ✦
Cadmium-induced renal dysfunction: New mechanism, treatment and prevention
✍ Scribed by Kazuo Nomiyama; Hiroko Nomiyama
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 276 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0896-548X
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Citrinin depresses the phosphorylation efficiency of rat renal cortical mitochondria, as inferred from the decrease of the respiratory control coefficient (RC) and ADP/O ratios. The transmembrane potential (A+) developed by energized mitochondria and the depolarization upon ADP addition are also dec