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Cadinene Derivatives from Eupatorium adenophorum

✍ Scribed by Ming-Zhong Wang; Yan-Yan Zhang; Shun-Lin Li; Xiang-Hai Cai; Xiao-Dong Luo

Publisher
John Wiley and Sons
Year
2006
Tongue
German
Weight
82 KB
Volume
89
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

A new norsesquiterpene named eupatorone (= (4__S__,4__aR__,6__R__)‐1‐acetyl‐6‐(acetyloxy)‐4,4a,5,6‐tetrahydro‐4,7‐dimethylnaphthalen‐2(3__H__)‐one; 1) and a new sesquiterpene derivative named 2‐deoxo‐2‐(acetyloxy)‐9‐oxoageraphorone (= (1__R__,4__S__,4a__R__,6__R__,8a__S__)‐6‐(acetyloxy)‐3,4,4a,5,6,8a‐hexahydro‐4,7‐dimethyl‐1‐(1‐methylethyl)naphthalen‐2(1__H__)‐one; 2), together with the five known cadinene derivatives 3–7 were isolated from the flower of Eupatorium adenophorum (Spreng.). Their structures were established by extensive NMR experiments, including 1D and 2D NMR.

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