A Novel Norditerpene from Eupatorium adenophorum.
✍ Scribed by Ming-Zhong Wang; Xiang-Hai Cai; Guo-Shun Du; Xiao-Dong Luo
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 12 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract __Eupatorium adenophorum__ leaves cause hepatotoxicity and cholestasis in rats. The hepatotoxicant has been characterized as 9‐oxo‐10,11‐dehydroageraphorone (ODA), a cadinene sesquiterpene. Oral administration of ODA, mixed in feed to rats, caused jaundice in 24 h. The liver of the into