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Ca2+entry but not Ca2+release is necessary for desensitization of ETAreceptors in airway epithelial cells

โœ Scribed by T. Meyer; M. Oles; L. Pott


Book ID
105878568
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
101 KB
Volume
361
Category
Article
ISSN
0028-1298

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The release of [ 3 H] arachidonic acid (AA) and its connection with the triggering of the MAP kinase cascade were studied in the human A549 epithelial cell line upon stimulation with thapsigargin. Thapsigargin can increase AA release along with the increase of intracellular calcium concentration, ph