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Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2

โœ Scribed by Maulilio J. Kipanyula; Laura Contreras; Enrico Zampese; Cristian Lazzari; Andrea K. C. Wong; Paola Pizzo; Cristina Fasolato; Tullio Pozzan

Book ID
117954480
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
452 KB
Volume
11
Category
Article
ISSN
1474-9718

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## Abstract Alzheimer's disease (AD) is characterized by progressive cognitive impairment. The effect of presenilin 1 (PS1) and PS2 mutation on cognition has been well characterized in a variety of transgenic mice. However, noncognitive behaviors have not been considered in these mice. In the prese