Ca2+ dependent activation and inactivation of Ca2+ release channels in the sarcoplasmic reticulum of cardiac and skeletal muscle
โ Scribed by Seiko Kawano; Cheol Joo Lee; Roberto Coronado
- Book ID
- 115981687
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 88 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-2828
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Rapid mixing-vesicle ion flux and planar lipid bilayer-single channel measurements have shown that a high-conductance, ligand-gated Ca2+ release channel is present in 'heavy', junctional-derived membrane fractions of skeletal and cardiac muscle sarcoplasmic reticulum. Using the release channel-speci
Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an