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Ca2+ channel agonist BAY-k 8644 does not elicit Ca2+ release from skeletal muscle sarcoplasmic reticulum

โœ Scribed by Francesco Zorzato; Pompeo Volpe; Giovanni Salviati; Alfredo Margreth

Book ID
115917008
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
408 KB
Volume
186
Category
Article
ISSN
0014-5793

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Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an