Abnormal human sarcoplasmic reticulum Ca2+ release channels in malignant hyperthermic skeletal muscle
β Scribed by Fill, M.; Stefani, E.; Nelson, T.E.
- Book ID
- 119409728
- Publisher
- Biophysical Society
- Year
- 1991
- Tongue
- English
- Weight
- 844 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0006-3495
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Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an
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