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Ca2+-calmodulin inhibits tail-anchored protein insertion into the mammalian endoplasmic reticulum membrane

✍ Scribed by Sarah Haßdenteufel; Nico Schäuble; Patrizia Cassella; Pawel Leznicki; Anika Müller; Stephen High; Martin Jung; Richard Zimmermann


Book ID
113622769
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
739 KB
Volume
585
Category
Article
ISSN
0014-5793

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The synthesis of biological membranes requires the insertion of proteins into a lipid bilayer. The rough endoplasmic reticulum of eukaryotic cells is a principal site of membrane biogenesis. The insertion of proteins into the membrane of the endoplasmic reticulum is mediated by a resident proteinace