✦ LIBER ✦

Membrane protein insertion into the endoplasmic reticulum - another channel tunnel?

✍ Scribed by Stephen High

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 759 KB
Volume: 14
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.950140807

No coin nor oath required. For personal study only.

✦ Synopsis

The synthesis of biological membranes requires the insertion of proteins into a lipid bilayer. The rough endoplasmic reticulum of eukaryotic cells is a principal site of membrane biogenesis. The insertion of proteins into the membrane of the endoplasmic reticulum is mediated by a resident proteinaceous machinery. Over the last five years several different experimental approaches have provided information about the components of the machinery and how it may function. cylosol Membrme L"11,W

📜 SIMILAR VOLUMES

Cotranslational integration of myelin pr

Cotranslational integration of myelin proteolipid protein (PLP) into the membrane of endoplasmic reticulum: Analysis of topology by glycosylation scanning and protease domain protection assay

✍ Stephan Wahle; Wilhelm Stoffel 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 136 KB 👁 1 views

The four transmembrane domain topology of the proteolipid protein (PLP) in the myelin membrane of the central nervous system (CNS) has been further substantiated by biochemical studies. We have analyzed the cotranslational polytopic integration of nascent PLP during protein synthesis into the membra