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Ca2+ and Zn2+ bind to different sites and induce different conformational changes in human calcyclin

✍ Scribed by Jolanta Kordowska; Walter F. Stafford; C.-L. Albert Wang


Book ID
114429039
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
295 KB
Volume
253
Category
Article
ISSN
1432-1327

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The interaction of Mg2+, Ca2+, Zn2+, and Cd2' with calf thymus DNA has been investigated by Raman spectroscopy. These spectra reveal that all of these ions, and particularly Zn2+, bind to phosphate groups of DNA, causing a slight structural change in the polynucleotide at very small metal : D N A (