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Ca handling during excitation–contraction coupling in heart failure

✍ Scribed by Zima, Aleksey V.; Bovo, Elisa; Mazurek, Stefan R.; Rochira, Jennifer A.; Li, Weiyan; Terentyev, Dmitry


Book ID
125347352
Publisher
Springer
Year
2014
Tongue
English
Weight
873 KB
Volume
466
Category
Article
ISSN
0031-6768

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Excitation-contraction coupling in heart
✍ W. J. Lederer; M. B. Cannell; N. M. Cohen; J. R. Berlin 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 381 KB

We have investigated the links between electrical excitation and contraction in mammalian heart muscle. Using isolated single cells from adult rat ventricle, a whole-cell voltage-clamp technique and quantitative fluorescence microscopy, we have measured simultaneously calcium current (ICa) and [Ca2+